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Clin Ultrasound > Accepted Articles
Keratinizing Squamous cell carcinoma of Gallbladder Presenting as Hepatic Abscess
Seul Ki Han1 , Taeyeong Kim2, Moon young Kim1
1Department of Internal medicine, Yonsei University Wonju College of Medicine, Wŏnju, Korea
2Department of Pathology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea, Won, Korea
Address for Correspondence:  Seul Ki Han ,Tel: 01074021590, Fax: 33-741-0951, Email: lolhsk@naver.com
Received: 28 October 2024;  Accepted: 9 November 2024.  Published online: 9 November 2024.
ABSTRACT
Gallbladder tumors are rare but aggressive malignancies, often identified incidentally through histopathological assessment after cholecystectomy. Adenocarcinoma is the most common phenotype, though Squamous cell carcinoma is rare, and it ranged as 1-4% of reported gallbladder cancer. Due to the rarity of the disease, early diagnosis is often challenging. One of the uncommon presentations of gallbladder cancer is hepatic abscess, with few cases reported in the literature. This report presents a rare case of an 82-year-old male referred with hepatic abscess. Multiple pathogens were isolated from the abscess, indicating a superimposed bacterial infection. Upon further investigation, cytology confirmed the presence of a keratinizing squamous carcinoma of gallbladder infiltrating the liver. This case presents a rare instance of squamous cell gallbladder carcinoma, which is difficult to diagnose, discovered in an elderly patient who presented with a liver abscess accompanied by bacterial infection. It highlights the challenges in diagnosis and treatment, as well as the poor prognosis associated with the condition.
Keywords: gallbladder cancer; squamous cell carcinoma; liver abscess
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